Renal complications of non-steroidal anti-inflammatory drugs (NSAID)

[Non-steroidal anti-inflammatory drugs (NSAID)].

Cardiovascular complications of non-steroidal anti-inflammatory drugs.

Coxibs, such as rofecoxib, celecoxib, and valdecoxib, selectively inhibit cyclooxygenase (COX)-2, the mainly inducible, pro-inflammatory COX isoform. Unlike traditional non-steroidal anti-inflammatory drugs (NSAIDs) most coxibs do not significantly inhibit COX-1 and are therefore less toxic to the gastrointestinal tract. Hence, coxibs widely replaced traditional NSAIDs for treatment of arthriti...

Non-steroidal anti-inflammatory drugs.

Renal impairment in relation to non-steroidal anti-inflammatory drugs.

Correspondence Renal impairment in relation to non-steroidal anti-inflammatory drugs SIR, Unsworth et al have recently shown that asymptomatic, reversible impairment of renal function is common in patients with rheumatoid arthritis (RA) receiving long term non-steroidal anti-inflammatory drug (NSAID) treatment .' This conclusion was derived from the observation that when NSAID treatment in 11 p...

Renal impairment associated with non-steroidal anti-inflammatory drugs

SIR, The study by Unsworth et al' would appear to have methodological deficiencies which limit both its conclusions and its applicability to rheumatic patients taking nonsteroidal anti-inflammatory drugs (NSAIDs). These include the reason for choosing to discontinue the medication in a particular individual; the lack of information about the reason for admission of the patients, and particularl...