Release Test of Indomethacin Suppository from Macrogol Bases
نویسندگان
چکیده
منابع مشابه
Severe colitis due to indomethacin suppository.
Colitis occurs with exposure to various chemicals, including alcohol, radiocontrast agents, glutaraldehyde, formalin, ergotamine, hydrogen peroxide and drugs (1). Frequency of colitis induced by drugs is often under estimated. Antibiotics, 5-fluorouracil (5-FU), hydroxycarbamide, nonsteroidal anti-inflammatory drugs (NSAIDS) and aspirin are usually incriminated (2-4). We report the case of seve...
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Background. Renal colic is a medical emergency due to the rapid onset and devastating nature of its pain. Opioids and nonsteroidal anti-inflammatory drugs (NSAIDs) are both used as first-line choices in its management. Aim. This study aimed to compare the efficacy and safety of opioids and NSAIDs in the management of acute renal colic. Methods. One hundred and fifty-eight patients were divided ...
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Suppositories are important tools for individual therapy, especially in paediatrics, and an instrumental assay method has become necessary for the quality control of dosage units. The aim of this work was to develop a rapid, effective high-performance liquid chromatography method to assay aminophenazone in extemporaneous suppositories prepared with two different suppository bases, adeps solidus...
متن کاملThe in Vitro Release of Indomethacin from Suppositories: Effects of Bases and Comparison of Different Dissolution Methods.
The suitability of apparatuses for the quality control of indomethacin (IND, 50 mg) compounded suppositories was evaluated and the effects of the type of suppository base on release profiles was investigated. The release characteristics of hydrophilic and lipophilic suppositories containing IND were compared using four types of dissolution methods: basket (RB), paddle (PD), dialysis tubing (DT)...
متن کاملEffect of Cold in Combination with Indomethacin Suppository Administration on Analgesic Need after Chest Tube Removal
Background and Objectives: Chest tube removal is a prompt painful procedure. The pain is gradually relieved after removal of the tube. Cold application in combination with the Indomethacin suppository administration may increase the duration for analgesic need. This study aimed to evaluate the effect of cold in combination with Indomethacin suppository on the duration for analgesic need after c...
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ژورنال
عنوان ژورنال: Japanese Journal of Hospital Pharmacy
سال: 1982
ISSN: 2185-9477,0389-9098
DOI: 10.5649/jjphcs1975.8.294