‘Relax and Repair’ to restrain aging
نویسندگان
چکیده
منابع مشابه
‘Relax and Repair’ to restrain aging
The maintenance of genomic integrity requires the precise identification and repair of DNA damage. Since DNA is packaged and condensed into higher order chromatin, the events associated with DNA damage recognition and repair are orchestrated within the layers of chromatin. Very similar to transcription, during DNA repair, chromatin remodelling events and histone modifications act in concert to ...
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Merge-and-shrink abstraction (M&S) is an approach for constructing admissible heuristic functions for cost-optimal planning. It enables the targeted design of abstractions, by allowing to choose individual pairs of (abstract) states to aggregate into one. A key question is how to actually make these choices, so as to obtain an informed heuristic at reasonable computational cost. Recent work has...
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ژورنال
عنوان ژورنال: Aging
سال: 2011
ISSN: 1945-4589
DOI: 10.18632/aging.100399