Relationship Between Obesity and B-Type Natriuretic Peptide Levels

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Relationship between N-terminal pro-B-type natriuretic peptide levels and metabolic syndrome

INTRODUCTION Previous studies have shown that obese individuals have reduced natriuretic peptide levels. But conflicting data exist on the relation of natriuretic peptide levels to other metabolic risk factors. MATERIAL AND METHODS We investigated the relationship between plasma N-terminal pro-B-type natriuretic peptide levels (NT-proBNP) and metabolic syndrome (MetS) and metabolic risk facto...

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Obesity and suppressed B-type natriuretic peptide levels in heart failure.

OBJECTIVES This investigation evaluated the relationship between obesity and B-type natriuretic peptide (BNP) in heart failure. BACKGROUND Obesity is a major risk factor for the development of heart failure, but the precise mechanisms remain uncertain. Physiologically, natriuretic peptides and lipolysis are closely linked. METHODS A total of 318 patients with heart failure were evaluated be...

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Effect of obesity on B-type natriuretic peptide levels in patients with pulmonary arterial hypertension.

Brain natriuretic peptide (BNP) levels are lower in obese patients with left ventricular failure than in their comparably ill, leaner counterparts. The effect of obesity on BNP in patients with pulmonary arterial hypertension (PAH) is unknown. We reviewed our prospective PAH registry data collected from November 2001 to December 2007 for patients undergoing right heart catheterization who met t...

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B-type natriuretic peptide serum levels in acute heart failure.

We read with great interest the article by Cowie et al.1 on clinical applications of the assessment of B-type natriuretic peptide (BNP). This is an important subject and the article also helps to clarify which areas of BNP research need more attention. The authors conclude that in new patients presenting to emergency services with dyspnoea, if the BNP level is <100 pg/mL, then heart failure is ...

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ژورنال

عنوان ژورنال: Archives of Internal Medicine

سال: 2004

ISSN: 0003-9926

DOI: 10.1001/archinte.164.20.2247