Relationship Between Atopy and Bronchial Hyperresponsiveness

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Relationship Between Atopy and Bronchial Hyperresponsiveness

Both atopy and bronchial hyperresponsiveness (BHR) are characteristic features of asthma. They are also found among non-asthmatic subjects, including allergic rhinitis patients and the general population. Atopy and BHR in asthma are closely related. Atopy induces airway inflammation as an IgE response to a specific allergen, which causes or amplifies BHR. Moreover, significant evidence of the c...

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Bronchial hyperresponsiveness and adult onset wheeze: the influence of atopy.

The commonly held belief that adult onset wheezing illness is primarily nonatopic in nature suggests that the role of atopy in the pathophysiology of bronchial hyperresponsiveness (BHR) in adult onset wheeze may be minimal. This study examined risk factors for BHR (BHR: provocative dose causing a 20% fall in forced expiratory volume in one second PD20 < or =16.38 micromol methacholine) among 82...

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The relationship between bronchial immunopathology and hyperresponsiveness in asthma.

Physiological and Immunopathological parameters were investigated in 15 patients with diagnosed asthma, and 6 non-asthmatics presenting with other chest symptoms. The 15 symptom-free asthmatics expressed bronchohyperresponsiveness with a mean provocative dose producing a 20% fall in forced expiratory volume in one second (PD20FEV1) of 1 mg histamine. None of the non-asthmatics responded to 16 m...

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Asthma: Respiratory Symptoms, Atopy and Bronchial Hyperresponsiveness in Young Adults in Estonia and Sweden

Jõgi, R. 2001. Asthma: Respiratory Symptoms, Atopy and Bronchial Hyperresponsiveness in Young Adults in Estonia and Sweden. Acta Universitatis Upsaliensis. Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine 1076. 64 pp. Uppsala. ISBN 91-554-5119-5. Morbidity of asthma has increased over the world. The reasons for this increase have remained unclear. Studies in childre...

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Prevalence of respiratory symptoms, bronchial hyperresponsiveness and atopy among adults: west and east Germany.

The prevalence of respiratory symptoms, atopic sensitization and bronchial hyperresponsiveness was compared in a random sample of adults, 20-44 yrs of age, in two cities in West and East Germany, Hamburg and Erfurt, respectively. There were much higher levels of outdoor air pollution due to sulphur dioxide and suspended particulates in Erfurt, and major differences in living conditions during t...

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ژورنال

عنوان ژورنال: Allergy, Asthma & Immunology Research

سال: 2013

ISSN: 2092-7355,2092-7363

DOI: 10.4168/aair.2013.5.4.181