Relapse after Antiepileptic Drug Withdrawal

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منابع مشابه

Long term course of childhood epilepsy following relapse after antiepileptic drug withdrawal.

OBJECTIVE To explore the course of epilepsy following relapse after antiepileptic drug (AED) withdrawal. METHODS Forty two patients were identified with onset of epilepsy in childhood in whom AEDs had been withdrawn after at least 2 years of seizure freedom, and in whom a relapse had occurred. Two patients were lost to follow up. RESULTS Median follow up after AED withdrawal was 5.9 years (...

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Prognostic tests and antiepileptic drug withdrawal after epilepsy surgery.

Approximately one in three patients with a successful epilepsy surgery will have seizure recurrence following antiepileptic drugs (AED) withdrawal. The value of postoperative testing for predicting seizure relapse after AED tapering is not clear. The purpose of this study was to review the literature for evidence on the use of postoperative investigations before AED discontinuation after succes...

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Antiepileptic Drug Withdrawal in Dogs with Epilepsy

Epilepsy is one of the most common neurological disorders in dogs and is treated by chronic administration of antiepileptic drugs (AEDs). In human beings with epilepsy, it is common clinical practice to consider drug withdrawal after a patient has been in remission (seizure free) for three or more years, but withdrawal is associated with the risk of relapse. In the present study, the consequenc...

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Cortical excitability during prolonged antiepileptic drug treatment and drug withdrawal.

OBJECTIVE Previous reports characterized the effects of administration of single oral doses of antiepileptic drugs (AED) on cortical excitability. However, AED effects on cortical excitability, and their relationship to plasma blood levels, during chronic drug administration at therapeutic doses are not known. The objective of the study was to determine whether plasma blood levels during chroni...

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Antiepileptic drugs and relapse after epilepsy surgery.

PURPOSE To evaluate whether the postoperative, antiepileptic drug (AED) regimen influences seizure recurrence after anterior temporal lobectomy when considering the putative mechanism of action and possible neuroprotective effects. METHODS This was a retrospective study. Patients who had an anterior temporal lobectomy for refractory epilepsy, whose preoperative MRI indicated mesial temporal s...

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ژورنال

عنوان ژورنال: Pediatric Neurology Briefs

سال: 1989

ISSN: 2166-6482,1043-3155

DOI: 10.15844/pedneurbriefs-3-11-5