Rehydrated Lyophilized Rifampicin-Loaded mPEG–DSPE Formulations for Nebulization
نویسندگان
چکیده
منابع مشابه
Formulation of rifampicin-cyclodextrin complexes for lung nebulization.
Lung administration of antibiotics by nebulization is promising for improving treatment efficiency for pulmonary infections, as it increases drug concentration at sites of infection while minimizing systemic side effects. For poorly soluble molecules like rifampicin, cyclodextrins (CD) may improve lung delivery by permitting higher dosing. For this purpose, we investigated rifampicin-CD complex...
متن کاملEffect of Formulation Variables on Rifampicin Loaded Alginate Beads
The present work investigated the preparation of biodegradable beads with alginate polymer by ionotropic gelation method to improve the control release properties of the antibiotic rifampicin. Ionotropic gelation method was applied to prepare beads using calcium chloride (CaCl2) as cationic component and alginate as an anionic component. In this method, adding 0.5% w/v polyvinyl alcohol (PVA) t...
متن کاملFeeding Triatomines (Hemiptera: Reduviidae) with lyophilized and rehydrated blood, under laboratory conditions.
The aim of the present work was to examine the possibility of feeding Triatominae (Hemiptera: Reduviidae) on rehydrated lyophilized blood, rather than with heparinated or defibrinated blood which are more commonly used in the artificial rearing of these insects (ES Garcia et al. 1975 An Acad Bras Ciênc 47: 537-545, MM Lima et al. 1989 Mem Inst Oswaldo Cruz 84: 112, JR Mac Cord et al. 1990 Rev B...
متن کاملEffect of Formulation Variables on Rifampicin Loaded Alginate Beads
The present work investigated the preparation of biodegradable beads with alginate polymer by ionotropic gelation method to improve the control release properties of the antibiotic rifampicin. Ionotropic gelation method was applied to prepare beads using calcium chloride (CaCl2) as cationic component and alginate as an anionic component. In this method, adding 0.5% w/v polyvinyl alcohol (PVA) t...
متن کاملPreservation of hemostatic and structural properties of rehydrated lyophilized platelets: potential for long-term storage of dried platelets for transfusion.
Currently, therapeutic platelet concentrates can be stored for only 5 days. We have developed a procedure that permits long-term storage of fixed and lyophilized platelets that retain hemostatic properties after rehydration. These rehydrated lyophilized platelets (RL platelets) restore hemostasis in thrombocytopenic rats and become incorporated in the hemostatic plug of bleeding time wounds of ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: AAPS PharmSciTech
سال: 2010
ISSN: 1530-9932
DOI: 10.1208/s12249-010-9428-6