REHABILITATION THERAPY WITH INSULIN-LIKE GROWTH FACTOR AFTER ACUTE SKELETAL MUSCLE INJURY

ABSTRACT Introduction Skeletal muscle injuries account for 10% to 50% of treadmill sports injuries. Insulin-like growth factor (IGF) is a family polypeptides with both insulin-like anabolic and growth-promoting effects. Sports play vital role in the recovery skeletal Objective The paper analyzes ability 1 (IGF-1) repair injury caused by exercise. Method We injected drugs under wound after exercise-induced rats. control group was saline, experimental an factor. conduct histological electron microscopic structural analysis rats, Results: After injury, formed basal lamina protective film earlier than group, activated myoblasts, myofilaments, myotubes, fused into fibers group. healing quality also better. endogenous. mRNA content sex IGF-1 IGF-2 increased Conclusion Local injection exogenous factor-1 can stimulate proliferation myoblasts accelerate post-traumatic process sports. Level evidence II; Therapeutic studies - investigation treatment results.