Regulatory T Cells Promote Natural Killer Cell Education in Mixed Chimeras
نویسندگان
چکیده
منابع مشابه
T cell regulation of natural killer cells
In light of their role in the immune response against tumors and viruses, natural killer (NK) cells represent a promising target for immunotherapy. Before this target is reached, the various mechanisms that control NK cell activity must first be identified and understood. In the past decades, studies have identified two critical processes that prevent spontaneous NK cell-mediated autoimmune act...
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Understanding the mechanisms that help promote protective immune responses to pathogens is a major challenge in biomedical research and an important goal for the design of innovative therapeutic or vaccination strategies. While natural killer (NK) cells can directly contribute to the control of viral replication, whether, and how, they may help orchestrate global antiviral defense is largely un...
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ژورنال
عنوان ژورنال: American Journal of Transplantation
سال: 2017
ISSN: 1600-6135
DOI: 10.1111/ajt.14342