Regulation of Th17 Differentiation by IKKα-Dependent and -Independent Phosphorylation of RORγt
نویسندگان
چکیده
منابع مشابه
Transcriptional regulation of the Th17 immune response by IKKα
Th17 cells are a subset of T cells that play crucial roles in the pathogenesis of many inflammatory diseases. We report here the identification of IKKα (inhibitor of NF-κB kinase-α) as a key transcriptional regulator of the Th17 lineage. T cells expressing a nonactivatable form of IKKα were significantly compromised in their ability to produce IL-17 and to initiate neural inflammation. IKKα is ...
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این تحقیق از دو قسمت اصلی تشکیل شده است: در قسمت اول فراگیری ختمیت به ویژه درک و تولید اینگونه جملات توسط فراگیران ایرانی زبان انگلیسی مورد بررسی قرار گرفته است. قضاوت تعدادی انگلیسی زبان بر روی این جملات نیز هدفی دیگر بود که در این رساله بررسی شده است. از موضوعات دیگر تفاوت بین نشانه های ختمیت در زبان انگلیسی و فارسی و تاثیر زبان اول فراگیران در درک و تولید اینگونه جملات است. در قسمت دوم استفا...
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ژورنال
عنوان ژورنال: The Journal of Immunology
سال: 2017
ISSN: 0022-1767,1550-6606
DOI: 10.4049/jimmunol.1700457