منابع مشابه
Sympathetic input into the enteric nervous system.
Introduction The basic concepts of the autonomic nervous system of organs and tissues were formulated around the turn of the century and summarised in a classical monograph by Langley (1921). The detailed distribution of the sympathetic nerves was, however, not elucidated until it became possible to stain sympathetic neurones specifically using the FalckHillarp technique. When this technique wa...
متن کاملDevelopment of the enteric nervous system.
Development of the ENS requires the function of a diverse set of genes encoding transcription factors, signaling molecules, and their receptors. Mutations of these genes result in altered ENS function in animals and humans. In particular, such mutations have been shown to contribute to many cases of Hirschsprung's disease. Elucidation of the mechanisms of ENS development and function allow the ...
متن کاملDevelopment of the zebrafish enteric nervous system.
The enteric nervous system (ENS) is composed of neurons and glia that modulate many aspects of intestinal function. The ability to use both forward and reverse genetic approaches and to visualize development in living embryos and larvae has made zebrafish an attractive model in which to study mechanisms underlying ENS development. In this chapter, we review the recent work describing the develo...
متن کاملEndoderm-derived Sonic hedgehog and mesoderm Hand2 expression are required for enteric nervous system development in zebrafish.
The zebrafish enteric nervous system (ENS), like those of all other vertebrate species, is principally derived from the vagal neural crest cells (NCC). The developmental controls that govern the migration, proliferation and patterning of the ENS precursors are not well understood. We have investigated the roles of endoderm and Sonic hedgehog (SHH) in the development of the ENS. We show that end...
متن کاملEmbryology and development of the enteric nervous system.
Origin and migration of neural crest derived cells in the gut The neurones and glial cells of the enteric nervous system (ENS) are derived from the neural crest (fig 1). While they are migrating, neural crest cells are morphologically indistinguishable from mesenchymal cells through which they migrate, and thus a variety of experimental approaches have been used to examine colonisation of the g...
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2010
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.24.1_supplement.300.4