Regulation of insulin secretion by the post-translational modifications

Post-translational modification (PTM) has a significant impact on cellular signaling and function regulation. In pancreatic β cells, PTMs are involved in insulin secretion, cell development, viability. The dysregulation of PTM cells is clinically associated with the development diabetes mellitus. Here, we summarized current findings major occurring their roles secretion. Our work provides comprehensive insight into understanding mechanisms secretion potential therapeutic targets for from perspective protein PTMs.