Regulation of growth: Epigenetic mechanisms?
نویسندگان
چکیده
منابع مشابه
Epigenetic mechanisms of regulation of Foxp3 expression.
Regulatory T cells play important roles in the control of autoimmunity and maintenance of transplantation tolerance. Foxp3, a member of the forkhead/winged-helix family of transcription factors, acts as the master regulator for regulatory T-cell (Treg) development and function. Mutation of the Foxp3 gene causes the scurfy phenotype in mouse and IPEX syndrome (immune dysfunction, polyendocrinopa...
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DNA replication involves the chromatin assembly on new DNA strands which involves the formation of new nucleosomes, the basic unit of chromatin. Nucleosome is composed of the tetramer of H3/H4 histones and two dimers of histones H2A/ H2B that are wrapped around with DNA segment [1,2]. H3/ H4 and H2A/H2B histones are called core histones as they are positioned in the center of nucleosome. Some c...
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ژورنال
عنوان ژورنال: Annales d'Endocrinologie
سال: 2017
ISSN: 0003-4266
DOI: 10.1016/j.ando.2017.04.004