Regulation of an RNA granule during spermatogenesis: acetylation of MVH in the chromatoid body of germ cells
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چکیده
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Regulation of an RNA granule during spermatogenesis: acetylation of MVH in the chromatoid body of germ cells.
During mammalian spermatogenesis, the mouse VASA homolog (MVH; also known as DDX4), a germ-cell-specific DEAD-box type RNA-binding protein, localizes in a germline-specific RNA granule termed the chromatoid body (CB). Genetic analyses have revealed that MVH is essential for progression through spermatogenesis, although the molecular mechanisms of its function remain elusive. We found that the a...
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ژورنال
عنوان ژورنال: Journal of Cell Science
سال: 2011
ISSN: 1477-9137,0021-9533
DOI: 10.1242/jcs.096461