Regulation of actin cytoskeleton dynamics by Arf-family GTPases
نویسندگان
چکیده
منابع مشابه
P120 Catenin Regulates the Actin Cytoskeleton via Rho Family Gtpases
Cadherins are calcium-dependent adhesion molecules responsible for the establishment of tight cell-cell contacts. p120 catenin (p120ctn) binds to the cytoplasmic domain of cadherins in the juxtamembrane region, which has been implicated in regulating cell motility. It has previously been shown that overexpression of p120ctn induces a dendritic morphology in fibroblasts (Reynolds, A.B. , J. Dani...
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Arfs are a family of Ras-related GTP-binding proteins that function in the regulation of membrane trafficking and structure. The six mammalian Arf proteins are expressed ubiquitously and so it is anticipated that each will have a distinct localization and function within the cell. It has been assumed that much of this specificity will be defined by determining which regulators of Arfs, the GEFs...
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ژورنال
عنوان ژورنال: Trends in Cell Biology
سال: 2008
ISSN: 0962-8924
DOI: 10.1016/j.tcb.2008.02.002