Regulated endocytosis of NCC

نویسندگان

چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Regulated endocytosis of NCC.

THE THIAZIDE-SENSITIVE Na -Cl cotransporter (NCC) in the aldosterone-sensitive distal convoluted tubule (DCT) is responsible for the reabsorption of as much as 10% of filtered Na -Cl (13). Notably, this may be a significant overestimate of the quantitative contribution of NCC to renal Na -Cl handling, in light of the recent demonstration that combined activity of the apical Na -dependent Cl -HC...

متن کامل

Activity-Regulated N-Cadherin Endocytosis

Enduring forms of synaptic plasticity are thought to require ongoing regulation of adhesion molecules, such as N-cadherin, at synaptic junctions. Little is known about the activity-regulated trafficking of adhesion molecules. Here we demonstrate that surface N-cadherin undergoes a surprisingly high basal rate of internalization. Upon activation of NMDA receptors (NMDAR), the rate of N-cadherin ...

متن کامل

Endocytosis, recycling, and regulated exocytosis of glucose transporter 4.

Glucose transporter 4 (GLUT4) is responsible for the uptake of glucose into muscle and adipose tissues. Under resting conditions, GLUT4 is dynamically retained through idle cycling among selective intracellular compartments, from whence it undergoes slow recycling to the plasma membrane (PM). This dynamic retention can be released by command from intracellular signals elicited by insulin and ot...

متن کامل

Endocytosis of cholera toxin by human enterocytes is developmentally regulated.

Many secretory diarrheas including cholera are more prevalent and fulminant in young infants than in older children and adults. Cholera toxin (CT) elicits a cAMP-dependent chloride secretory response in intestinal epithelia, which accounts for the fundamental pathogenesis of this toxigenic diarrhea. We have previously reported that the action of this bacterial enterotoxin is excessive in immatu...

متن کامل

Internet - Draft RIPE NCC

With the DS record [5] the concept of key-signing and zone-signing keys has been introduced. Key-signing keys are the keys that sign the keyset only. In general, key-signing keys are the keys that are pointed to by DS records and are the first keys to be used when following a chain of trust into the zone. The key-signing keys only sign the KEY RRset at the apex of a zone, zonesigning keys sign ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: American Journal of Physiology-Renal Physiology

سال: 2010

ISSN: 1931-857X,1522-1466

DOI: 10.1152/ajprenal.00280.2010