منابع مشابه
Structural bases of myocardial hypertrophy.
Hypertrophy is undoubtedly the most important problem in the structural adaptation of heart muscle. It stands at the centre of medical discussion because it is just the hypertrophic heart muscle that, after performing efficiently for a long time, finally fails. For this reason structural researches into hypertrophy include those of myocardial failure (Buchner, I950, I96I). According to the macr...
متن کاملExpressions of CD11a, CD11b, and CD11c integrin proteins in rats with myocardial hypertrophy
Objective(s):To examine the expressions of CD11a, CD11b, and CD11c integrins in the myocardial tissues of rats with isoproterenol-induced myocardial hypertrophy. This study also provided morphological data to investigate the signal transduction mechanisms of myocardial hypertrophy and reverse it. Materials and Methods: A myocardial hypertrophy model was established by subcutaneously injecting i...
متن کاملCollagen phenotypes during development and regression of myocardial hypertrophy in spontaneously hypertensive rats.
The myocardium contains collagen matrix that is a major determinant of its architecture, structural integrity, and mechanical properties. This fibrillar matrix consists primarily of type I and type III collagens having epimysial, perimysial, and endomysial components. The present study shows the alteration of collagen phenotypes during the evolution of hypertensive hypertrophy. Therapy with cap...
متن کاملImprovement in midwall myocardial shortening with regression of left ventricular hypertrophy.
Despite normal indices of left ventricular (LV) chamber function, patients with LV hypertrophy (LVH) due to hypertension are thought to have depressed midwall systolic shortening compared with normotensives. The aims of the present study were (1) to confirm this observation and (2) to assess the effects of antihypertensive therapy that cause regression of LVH on LV systolic function assessed at...
متن کاملRegression of myocardial hypertrophy after aortic valve replacement: faster in women?
BACKGROUND In patients with aortic stenosis, pressure overload induces cardiac hypertrophy and fibrosis. Female sex and estrogens influence cardiac remodeling and fibrosis in animal models and in men. Sex differences and their molecular mechanisms in hypertrophy regression after aortic valve replacement have not yet been studied. METHODS AND RESULTS We prospectively obtained preoperative and ...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 1974
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-197404000-00048