منابع مشابه
Regional Myocardial Blood Flow
Do oxygen-derived free radicals, generated at the time of reperfusion, lethally injure viable, previously ischemic myocardium, damage vascular endothelium, and impair recovery of postischemic contractile function? To address these issues, 23 anesthetized open-chest dogs underwent 2 hours of left anterior descending coronary artery occlusion followed by 4 hours of reperfusion. Immediately prior ...
متن کاملRegional Myocardial Blood Flow
nary artery disease has provided an intense stimulus for expansion of our present knowledge of the coronary circulation. In the experimental animal laboratory, the electromagnetic flowmeter has proved to be an excellent tool by which one can study dynamic aspects of the coronary circulation. A flowmeter is clearly unsuitable for human investigation; therefore, the search for a simple method of ...
متن کاملRegional Myocardial Blood Flow and Oxygen
sion. Arch Intern Med 133: 916-929, 1974 34. Bohr DF: Angiotensin on vascular smooth muscle. In Angiotensin, edited by IH Page, FM Bumpus. New York, Springer-Verlag, 1974, pp424-428 35. Williams GH, HollenbergNK, Braley LM: Influence of sodium intake on vascular and adrenal angiotensin II receptors. Endocrinology 98: 1343-1350, 1976 36. Fray FCS, Johnson MD, Barger AC: Renin release and pressor...
متن کاملMYOCARDIAL BLOOD FLOW Quantification of regional myocardial blood flow in vivo with H 2150
Using H,15O (half-life = 2.1 min) we demonstrated that a modification of the tissue autoradiographic approach permitted quantitation of myocardial blood flow in open-chest dogs by direct assay of myocardial tissue and that noninvasive estimation with positron-emission tomography (PET) delineated relative myocardial blood flow in intact dogs. ln open-chest anesthetized dogs, the single-pass extr...
متن کاملRelationship between regional myocardial procainamide concentration and regional myocardial blood flow during ischemia in the dog.
We measured myocardial blood flow and myocardial procainamide concentration in 24 sections of left ventricle following occlusion of the left circumflex coronary artery in 11 dogs. "C-Labeled procainamide was infused at a constant rate (40 jig/kg P r m ' n ) following completion of the coronary artery occlusion. At the end of 4 hours, the infusion was terminated and the dogs were killed. Regiona...
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ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 1967
ISSN: 0021-9738
DOI: 10.1172/jci105632