Regional changes in thalamic shape and volume with increasing age

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Regional changes in thalamic shape and volume with increasing age

The thalamus undergoes significant volume loss and microstructural change with increasing age. Alterations in thalamo-cortical connectivity may contribute to the decline in cognitive ability associated with aging. The aim of this study was to assess changes in thalamic shape and in the volume and diffusivity of thalamic regions parcellated by their connectivity to specific cortical regions in o...

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The thalamus is known to play a key role in arousal regulation and support of human consciousness. Neuropathological studies have identified thalamic damage as one of the most common abnormalities present in the brains of patients who were in a vegetative state (VS) or a minimally-conscious state (MCS) state at the time of their deaths. Nonetheless, no in vivo studies of thalamic abnormalities ...

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ژورنال

عنوان ژورنال: NeuroImage

سال: 2012

ISSN: 1053-8119

DOI: 10.1016/j.neuroimage.2012.07.043