Reflex Excitability Regulates Prepulse Inhibition
نویسندگان
چکیده
منابع مشابه
Reflex excitability regulates prepulse inhibition.
Presentation of a weak stimulus, a prepulse, before a reflex-evoking stimulus decreases the amplitude of the reflex response relative to reflex amplitude evoked without a preceding prepulse. For example, presenting a brief tone before a trigeminal blink-eliciting stimulus significantly reduces reflex blink amplitude. A common explanation of such data are that sensory processing of the prepulse ...
متن کاملDopaminergic Induced Changes in Mauthner-cell Excitability Disrupts Prepulse Inhibition
Dopaminergic induced changes in Mauthner-cell excitability disrupts prepulse inhibition 1 in the startle circuit of goldfish. 2 3 Violeta Medan and Thomas Preuss 4 5 Department of Psychology, Hunter College, City University of New York 6 695 Park Avenue, New York, NY 10065 7 8 Running head: dopaminergic disruption of prepulse inhibition 9 10 Corresponding author: Thomas Preuss, [email protected]...
متن کاملImpaired prepulse inhibition and prepulse-elicited reactivity but intact reflex circuit excitability in unmedicated schizophrenia patients: a comparison with healthy subjects and medicated schizophrenia patients.
Deficient sensorimotor gating as indexed by prepulse inhibition (PPI) of the startle response has been reported repeatedly in patients suffering from schizophrenia. According to the widely accepted "protective hypothesis," PPI reflects the protection of ongoing information processing against interference by other stimuli. Alternatively, it has been proposed that PPI might be regulated by startl...
متن کاملPrepulse-elicited startle in prepulse inhibition.
BACKGROUND Prepulse inhibition (PPI) has become a major experimental paradigm in the study of psychiatric disorders. In this study, a potential confound in measurement and interpretation of PPI, namely startle reactions to so-called "nonstartling" prepulses, was examined. METHODS Prepulses of 80, 85, and 90 dB(A) were presented on their own or followed by a pulse of 115 dB(A) (lead interval: ...
متن کاملPrepulse Inhibition of Acoustic Startle Reflex as a Function of the Frequency Difference between Prepulse and Background Sounds in Mice
BACKGROUND Prepulse inhibition (PPI) depicts the effects of a weak sound preceding strong acoustic stimulus on acoustic startle response (ASR). Previous studies suggest that PPI is influenced by physical parameters of prepulse sound such as intensity and preceding time. The present study characterizes the impact of prepulse tone frequency on PPI. METHODS Seven female C57BL mice were used in t...
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ژورنال
عنوان ژورنال: The Journal of Neuroscience
سال: 2000
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.20-11-04240.2000