Refining Risk Estimates in Hereditary Nonpolyposis Colorectal Cancer: Are We There Yet?
نویسندگان
چکیده
منابع مشابه
Hereditary nonpolyposis colorectal cancer.
Hereditary nonpolyposis colorectal cancer (HNPCC), or Lynch syndrome, is the most common form of hereditary colorectal cancer (CRC). A well-orchestrated cancer family history is essential for its diagnosis since, unlike its familial adenomatous polyposis (FAP) hereditary cancer counterpart, HNPCC lacks distinguishing clinical stigmata of its cancer genetic risk. Discoveries in the 1990s of germ...
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background: there are no data on familial aggregation of colorectal cancer (crc) in northeastern iran. the aim of this study was to determine the prevalence of early-onset crc and patients suspected for hereditary non-polyposis colorectal cancer (hnpcc) based on the clinical criteria in this area. materials and methods: documents were collected from two hospitals in mashhad regarding 326 inpati...
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ژورنال
عنوان ژورنال: JNCI Cancer Spectrum
سال: 2020
ISSN: 2515-5091
DOI: 10.1093/jncics/pkaa030