Reference Interval for Serum Cystatin C in Children

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Reference interval for serum cystatin C in children.

Serum creatinine and creatinine clearance are widely used as measures of glomerular filtration rate (GFR) in clinical medicine. Unfortunately, serum creatinine concentrations are not determined only by glomerular filtration (1 ). Alteration in renal handling and metabolism of creatinine and methodological interferences in its measurement may influence the concentrations of serum creatinine (2 )...

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A reference interval for serum IgG subclasses in Chinese children

BACKGROUND Reference intervals (RIs) for serum IgG subclasses vary greatly among different geographical regions. The present study aimed to establish RIs for serum IgG subclasses in Chinese children, which is essential for interpretation of laboratory findings and making clinical decisions. METHODS This study was performed in accordance with guideline C28-A3, proposed by the International Fed...

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Reference Intervals for Serum Cystatin C and Factors Influencing Cystatin C Levels Other than Renal Function in the Elderly

OBJECTIVE The present study aimed to establish reference intervals for serum cystatin C (Scys-C) stratified by stages of chronic kidney disease, explore factors influencing Scys-C and compare the performance of Scys-C with serum creatinine (Scr) in the young and elderly. METHODS A total of 800 participants, 516 young (<60 years) and 284 old (≥60 years) subjects were included in this study. Sc...

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Reference ranges for plasma cystatin C and creatinine measurements in premature infants, neonates, and older children.

AIM To establish a reference range in the paediatric population for the new glomerular filtration rate (GFR) marker, cystatin C, and to compare it with that of creatinine. METHODS Cystatin C and creatinine were measured by particle enhanced nephelometric immunoassay (PENIA) and fixed interval Jaff¿e methods, respectively, in 291 children aged 1 day to 17 years, including 30 premature infants ...

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New combined serum creatinine and cystatin C quadratic formula for GFR assessment in children.

BACKGROUND AND OBJECTIVES The estimated GFR (eGFR) is important in clinical practice. To find the best formula for eGFR, this study assessed the best model of correlation between sinistrin clearance (iGFR) and the solely or combined cystatin C (CysC)- and serum creatinine (SCreat)-derived models. It also evaluated the accuracy of the combined Schwartz formula across all GFR levels. DESIGN, SE...

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ژورنال

عنوان ژورنال: Clinical Chemistry

سال: 1999

ISSN: 0009-9147,1530-8561

DOI: 10.1093/clinchem/45.10.1856