Refactoring the Genetic Code for Increased Evolvability
نویسندگان
چکیده
منابع مشابه
Refactoring the Genetic Code for Increased Evolvability
The standard genetic code is robust to mutations during transcription and translation. Point mutations are likely to be synonymous or to preserve the chemical properties of the original amino acid. Saturation mutagenesis experiments suggest that in some cases the best-performing mutant requires replacement of more than a single nucleotide within a codon. These replacements are essentially inacc...
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ژورنال
عنوان ژورنال: mBio
سال: 2017
ISSN: 2161-2129,2150-7511
DOI: 10.1128/mbio.01654-17