Reduced-dose rasburicase (recombinant xanthine oxidase) in adult cancer patients with hyperuricemia
نویسندگان
چکیده
منابع مشابه
Effects of Recombinant Urate Oxidase (Rasburicase) and Allopurinol for Prophylaxis and Treatment of Hyperuricemia in Patients with Leukemia and Lymphoma
Background: Efficacy of rasburicase in pediatric patients with leukemia and lymphoma is proved. This study aims toweigh efficacy and safety of rasburicase versus more conventional therapy, allopurinol, and to compare their safetyand properties in tumor lysis syndrome (TLS) of leukemia and lymphoma patients.Materials and Methods: The study was done with a retrospective cohort design. Patients we...
متن کاملComparison of Xanthine Oxidase Inhibitors in Gouty Patients with Hyperuricemia
Objective: Febuxostat is more effective/superior to Allopurinol in reducing the serum uric acid (SUA) level in the treatment of hyperuricemic with gout. Methods: This randomized control study included 200 hyperuricemic patients with gout, at Multi-center study including Outdoor Departments of Medicine from four different hospitals of Lahore, Pakistan. Patients age range 18-50 years diagnosis wi...
متن کاملeffects of recombinant urate oxidase (rasburicase) and allopurinol for prophylaxis and treatment of hyperuricemia in patients with leukemia and lymphoma
background: efficacy of rasburicase in pediatric patients with leukemia and lymphoma is proved. this study aims toweigh efficacy and safety of rasburicase versus more conventional therapy, allopurinol, and to compare their safetyand properties in tumor lysis syndrome (tls) of leukemia and lymphoma patients.materials and methods: the study was done with a retrospective cohort design. patients we...
متن کاملEfficacy and safety of recombinant urate oxidase (rasburicase) for treatment and prophylaxis of hyperuricemia in children undergoing chemotherapy.
Rasburicase has been defined as a potent urolytic agent for management of malignancy-associated hyperuricemia. We reviewed the data of 26 children with malignancy at risk for TLS who received rasburicase for treatment or prophylaxis of acute hyperuricemia, producing a significant decrease in uric acid level in all the patients. Tolerance of treatment was excellent. Rasburicase is a safe, highly...
متن کاملPitfalls, prevention, and treatment of hyperuricemia during tumor lysis syndrome in the era of rasburicase (recombinant urate oxidase)
Along with hydration and urinary alkalinization, allopurinol has been the standard agent for the management of hyperuricemia in patients with a high tumor burden at risk of tumor lysis syndrome; however, this agent often fails to prevent and treat this complication effectively. Rasburicase (recombinant urate oxidase) has been shown to be effective in reducing uric acid and preventing uric acid ...
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ژورنال
عنوان ژورنال: Bone Marrow Transplantation
سال: 2006
ISSN: 0268-3369,1476-5365
DOI: 10.1038/sj.bmt.1705379