Reduced cerebral blood flow and oxygen metabolism in extremely preterm neonates with low-grade germinal matrix- intraventricular hemorrhage

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Reduced cerebral blood flow and oxygen metabolism in extremely preterm neonates with low-grade germinal matrix- intraventricular hemorrhage.

Low-grade germinal matrix-intraventricular hemorrhage (GM-IVH) is the most common complication in extremely premature neonates. The occurrence of GM-IVH is highly associated with hemodynamic instability in the premature brain, yet the long-term impact of low-grade GM-IVH on cerebral blood flow and neuronal health have not been fully investigated. We used an innovative combination of frequency-d...

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Cerebral Intraventricular Hemorrhage and Interleukin-6 in Preterm Neonates

Background: Intraventricular hemorrhage (IVH) in preterm neonates is a serious problem in neonatal intensive care units (NICU) worldwide. IVH is reported in approximately 60-70% of very-low-birth-weight (VLBW) neonates. The present study aimed to assess the association of IVH with neonatal characteristics and serum markers, such as serum Interleukin-6 (IL-6) level, in preterm neonates in an aca...

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Correlation Study of Various Factors with Germinal Matrix-Intraventricular Hemorrhage in Preterm Neonates

The objective of this paper was to study various maternal and neonatal factors in relation to germinal matrix hemorrhage in preterm neonates. It was a hospital based observational study. The subjects included 120 preterm neonates with ≤34 weeks gestation with birth weight between 500 gm to 1500 gm admitted in Neonatal Intensive Care Unit of SDMH Hospital. Various maternal and neonatal risk fact...

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Risk Factors Associated with Germinal Matrix-Intraventricular Hemorrhage in Preterm Neonates

OBJECTIVE The purpose of this study is to identify the risk factors associated with the development of germinal matrix-intraventricular hemorrhage (GM-IVH) and the relationship of the severity of disease and prematurity. METHODS A total of 168 premature neonates whose birth weight ≤1500 g or gestational age ≤34 weeks were examined by cranial ultrasound (CUS) for detection of GM-IVH among the ...

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Cerebral oxygenation in preterm infants with germinal matrix-intraventricular hemorrhages.

BACKGROUND AND PURPOSE Preterm infants are at risk of developing germinal matrix hemorrhages-intraventricular hemorrhages (GMH-IVH). Disturbances in cerebral perfusion are associated with GMH-IVH. Regional cerebral tissue oxygen saturation (r(c)SO₂), measured with near-infrared spectroscopy, and fractional tissue oxygen extraction (FTOE) were calculated to obtain an indication of cerebral perfu...

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ژورنال

عنوان ژورنال: Scientific Reports

سال: 2016

ISSN: 2045-2322

DOI: 10.1038/srep25903