Reduced γ-Aminobutyric AcidA–Benzodiazepine Binding Sites in Insular Cortex of Individuals With Panic Disorder
نویسندگان
چکیده
منابع مشابه
Reduced serotonin type 1A receptor binding in panic disorder.
Recent animal models suggest that disturbances in serotonin type-1A receptor (5-HT(1A)R) function may contribute to chronic anxiety, although it is not clear at all whether such models constitute relevant models for panic disorder (PD) in humans. The selective 5-HT(1A)R radioligand [18F]trans-4-fluoro-N-2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-N-(2-pyridyl)cyclohexanecarboxamide (FCWAY) perm...
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Background: One of the psychological disorders that rooted in anxiety is the panic disorder. There are a lot of studies about this disorder in adults, while fewer studies are assigned to panic disorder in children. This study reviews the available articles and tries to show the different parts of the disorder. Also, panic disorder in children is considered in terms of content, signs and treatme...
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Objective: Up to now, no investigation has applied a complementary approach in terms of the emotional and affective temperament to study Panic Disorder (PD), Post-Traumatic Stress Disorder (PTSD), and healthy controls. Hence the current study aimed to investigate the affective and emotional temperaments among individuals with PD, PTSD, and healthy controls using an integrative temperament scale...
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Social anxiety disorder (SAD) is the one of the most common anxiety disorders. Despite its high prevalence, the disorder is still considerably undiagnosed and untreated. The disease places a massive burden on patient’s lives, affecting not only their social interactions but also their educational and professional activities, thereby constituting a severe disability. γ-aminobutyric acid (GABA) s...
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OBJECTIVE Given the association between the pathophysiology of panic disorder and prefrontal cortex function, we aimed to perform a volumetric MRI study in patients with panic disorder and healthy controls focusing on the in vivo neuroanatomy of the OFC. METHODS Twenty right-handed patients with panic disorder and 20 right-handed healthy control subjects were studied. The volumes of whole bra...
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ژورنال
عنوان ژورنال: Archives of General Psychiatry
سال: 2007
ISSN: 0003-990X
DOI: 10.1001/archpsyc.64.7.793