Redistribution of GABAB(1) Protein and Atypical GABAB Responses in GABAB(2)-Deficient Mice
نویسندگان
چکیده
منابع مشابه
Redistribution of GABAB(1) protein and atypical GABAB responses in GABAB(2)-deficient mice.
GABAB receptors mediate slow synaptic inhibition in the nervous system. In transfected cells, functional GABAB receptors are usually only observed after coexpression of GABAB(1) and GABAB(2) subunits, which established the concept of heteromerization for G-protein-coupled receptors. In the heteromeric receptor, GABAB(1) is responsible for binding of GABA, whereas GABAB(2) is necessary for surfa...
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ژورنال
عنوان ژورنال: Journal of Neuroscience
سال: 2004
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.5635-03.2004