Red Blood Cell-Mediated Hypoxic Vasodilatation
نویسندگان
چکیده
منابع مشابه
Red blood cell-mediated hypoxic vasodilatation: a balanced physiological viewpoint.
A Balanced Physiological Viewpoint To the Editor: We were disappointed to read the editorial presented by Drs Gladwin and Schechter,1 which appeared in the same issue of Circulation Research as our article.2 We believe that the views reflected a selective bias from 1 of 2 camps that have posed diametrically opposite views. This editorial was simply another review on nitrite by these authors. We...
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Red blood cells (RBCs) have been ascribed an essential role in matching blood flow to local metabolic demand during hypoxic vasodilation. The vasodilatory function of RBCs evidently relies on the allosteric properties of hemoglobin (Hb), which couple the conformation of Hb to tissue oxygen tension (PO2) and thereby provide a basis for the graded vasodilatory activity that is inversely proportio...
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Hypoxia, which commonly associates with respiratory and cardiovascular diseases, provokes an acute inflammatory response. However, underlying mechanisms are not well understood. Here we report that red blood cells (RBCs) induce hypoxic inflammation by producing reactive oxygen species (ROS) that diffuse to endothelial cells of adjoining blood vessels. Real-time fluorescence imaging of rat and m...
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Hypoxia, which commonly associates with respiratory and cardiovascular diseases, provokes an acute inflammatory response. However, underlying mechanisms are not well understood. Here we report that red blood cells (RBCs) induce hypoxic inflammation by producing reactive oxygen species (ROS) that diffuse to endothelial cells of adjoining blood vessels. Real-time fluorescence imaging of rat and m...
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Abstract Background Thyroid hormones have a crucial role in metabolism and proliferation of blood cells. Thyroid dysfunction induces different effects on blood cells such as anemia, erythrocytosis leukopenia, thrombocytopenia, and in rare cases causes’ pancytopenia. It also alter RBC indices include MCV, MCH, MCHC and RDW. Thus this study attempted to evaluate effect of hypo & hyperthyroi...
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ژورنال
عنوان ژورنال: Circulation Research
سال: 2004
ISSN: 0009-7330,1524-4571
DOI: 10.1161/res.95.2.e8