Recursive partitioning for risk stratification in men undergoing repeat prostate biopsies

The prostate cancer risk stratification (ProCaRS) project: recursive partitioning risk stratification analysis.

BACKGROUND The Genitourinary Radiation Oncologists of Canada (GUROC) published a three-group risk stratification (RS) system to assist prostate cancer decision-making in 2001. The objective of this project is to use the ProCaRS database to statistically model the predictive accuracy and clinical utility of a proposed new multi-group RS schema. METHODS The RS analyses utilized the ProCaRS data...

Strategies for repeat prostate biopsies.

Urologists are routinely faced with the dilemma of a persistently worrisome clinical picture for prostate cancer in patients who have undergone prior negative ultrasound-guided prostate biopsies. Indications for repeat biopsy include sustained or worsening of the findings that prompted the initial biopsy; various derivations of prostate-specific antigen; and the histology from the initial biops...

8 Strategies for Repeat Prostate Biopsies

Repeat transrectal prostate biopsies in diagnosing prostate cancer.

UNLABELLED Patients with negative prostate biopsy and persistent suspicion of prostate cancer (PCa) can pose a serious diagnostic problem. The AIM of our study was to determine the frequency of PCa found on repeat prostate biopsy and the factors leading to higher possibility of cancer positive histological result. PATIENTS AND METHODS We studied retrospectively 113 patients (82 from Universit...

The meaning of sampling density in multiple repeat prostate biopsies

INTRODUCTION Extended transrectal ultrasound-guided prostate biopsy is a state-of-the-art tool for prostate cancer detection. Nevertheless, approximately 1/3 of cancers are missed when using this method and repeat biopsy sessions are often required. The aim of this study was to investigate how sampling density (a compound variable reflecting the number of biopsy cores and prostate volume) impac...