Recurrent Spontaneous Abortion (RSA) and Maternal KIR Genes: A Comprehensive Meta-Analysis
نویسندگان
چکیده
منابع مشابه
Maternal KIR repertoire is not associated with recurrent spontaneous abortion.
BACKGROUND In view of evidence suggesting an immunological cause of recurrent spontaneous abortions (RSA) and the large number of maternal natural killer (NK) cells present in the pregnant uterus, we investigated the genetic polymorphism of the killer cell immunoglobulin-like receptors (KIR) in women with RSA. METHODS KIR gene repertoire and KIR2DL4 (a receptor for HLA-G) genotyping were dete...
متن کاملEffectiveness of Leukocyte Immunotherapy in Primary Recurrent Spontaneous Abortion (RSA)
Background: Recurrent spontaneous abortion (RSA) is defined as three or more se-quential abortions before the twentieth week of gestation. There are evidences to sup-port an allo-immunologic mechanism for RSA. One of the methods for treatment of RSA is leukocyte therapy; however there is still controversy about effectiveness of this method. Objectives: To evaluate the effectiveness of leukocyte...
متن کاملIntravenous immunoglobulin therapy for recurrent spontaneous abortion: a meta-analysis.
PROBLEM Published randomized trials of the use of intravenous immunoglobulins (IVIG) as a treatment for recurrent spontaneous abortion (RSA) have produced conflicting results. The purpose of this study was to conduct a systematic review of the current evidence to evaluate the effectiveness of IVIG for RSA. METHOD OF STUDY After a thorough search of the literature, four randomized, double-blin...
متن کاملEffectiveness of leukocyte immunotherapy in primary recurrent spontaneous abortion (RSA).
BACKGROUND Recurrent spontaneous abortion (RSA) is defined as three or more sequential abortions before the twentieth week of gestation. There are evidences to support an allo-immunologic mechanism for RSA. One of the methods for treatment of RSA is leukocyte therapy; however there is still controversy about effectiveness of this method. OBJECTIVES To evaluate the effectiveness of leukocyte t...
متن کاملeffectiveness of leukocyte immunotherapy in primary recurrent spontaneous abortion (rsa)
background: recurrent spontaneous abortion (rsa) is defined as three or more se-quential abortions before the twentieth week of gestation. there are evidences to sup-port an allo-immunologic mechanism for rsa. one of the methods for treatment of rsa is leukocyte therapy; however there is still controversy about effectiveness of this method. objectives: to evaluate the effectiveness of leukocyte...
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ژورنال
عنوان ژورنال: JBRA Assisted Reproduction
سال: 2020
ISSN: 1518-0557
DOI: 10.5935/1518-0557.20190067