Recurrent SPECC1L–NTRK fusions in pediatric sarcoma and brain tumors
نویسندگان
چکیده
منابع مشابه
Recurrent PRDM10 gene fusions in undifferentiated pleomorphic sarcoma.
PURPOSE Undifferentiated pleomorphic sarcoma (UPS) is defined as a sarcoma with cellular pleomorphism and no identifiable line of differentiation. It is typically a high-grade lesion with a metastatic rate of about one third. No tumor-specific rearrangement has been identified, and genetic markers that could be used for treatment stratification are lacking. We performed transcriptome sequencing...
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UNLABELLED Background and Need for Novel Biomarkers: Brain tumors are the leading cause of death by solid tumors in children. Although improvements have been made in their radiological detection and treatment, our capacity to promptly diagnose pediatric brain tumors in their early stages remains limited. This contrasts several other cancers where serum biomarkers such as cancer antigen (CA) 19-...
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ژورنال
عنوان ژورنال: Molecular Case Studies
سال: 2020
ISSN: 2373-2865,2373-2873
DOI: 10.1101/mcs.a005710