Recombinant live Salmonella spp. for human vaccination against heterologous pathogens
نویسندگان
چکیده
منابع مشابه
Live recombinant Salmonella oral vaccine against avian influenza viruses.
In 1997, the avian influenza virus (AIV) subtype H5N1 was first reported to infect humans.1 Up to 3 March 2015, the cumulative number of confirmed human cases of H5N1 was 784, with 429 deaths. There is no evidence that H5N1 viruses can transmit efficiently from person to person.2 Therefore, the key to prevention of a human H5N1 pandemic is to first control the H5N1 virus in birds. Traditionally...
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against experimental visceral leishmaniasis D i s s e r t a t i o n zur Erlangung des akademischen Grades d o c t o r r e r u m n a t u r a l i u m II Acknowledgement First, I would like to thank Dr. Toni Aebischer for giving me the great opportunity to do my PhD in his lab at the University of Edinburgh. Furthermore I would like to thank the members of the Leishmania lab, but especially Dr. At...
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BACKGROUND Live attenuated simian immunodeficiency virus (SIV) vaccines represent the most effective means of vaccinating macaques against pathogenic SIV challenge. However, thus far, protection has been demonstrated to be more effective against homologous than heterologous strains. Immune correlates of vaccine-induced protection have also been difficult to identify, particularly those measurab...
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Ever since the late 1980’s, when grade A shell eggs were associated for the first time with cases of human illness caused by Salmonella enteritidis (Se), the commercial layer industry in the United States has been presented with numerous and variable difficulties in presenting its product, the table egg, for what it is: a completely natural food item of excellent nutritional value, with undoubt...
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Susceptibility breakpoints are crucial for prudent use of antimicrobials. This study has developed the first susceptibility breakpoint (MIC ≤ 0.25 μg/ml) for enrofloxacin against swine Salmonella spp. based on wild-type cutoff (COWT) and pharmacokinetic-pharmacodynamic (PK-PD) cutoff (COPD) values, consequently providing a criterion for susceptibility testing and clinical usage of enrofloxacin.
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ژورنال
عنوان ژورنال: FEMS Immunology and Medical Microbiology
سال: 2000
ISSN: 0928-8244
DOI: 10.1016/s0928-8244(99)00214-x