Recombinant follitropin alfa/lutropin alfa in fertility treatment
نویسندگان
چکیده
منابع مشابه
Recombinant follitropin alfa/lutropin alfa in fertility treatment
Recombinant human follicle stimulating hormone (rFSH) and luteinizing hormone (LH), also known as follitropin alpha and lutropin alpha, are manufactured by genetic engineering techniques which ensure high quality and batch to batch consistency. Follitropin alpha can be used for controlled ovarian hyperstimulation in assisted reproduction, ovulation induction for WHO group I and II anovulatory i...
متن کاملAdministration of follitropin alfa and lutropin alfa combined in a single injection: a feasibility assessment
BACKGROUND Gonadotrophins are routinely administered in assisted reproductive technology (ART) treatment protocols. Recombinant human follicle-stimulating hormone (r-hFSH; follitropin alfa) and recombinant human luteinizing hormone (r-hLH; lutropin alfa) can be administered individually or in a fixed combination. The ability to vary the FSH to LH dose ratio in a single injection without comprom...
متن کاملManaging infertility with the follitropin alfa prefilled pen injector – patient considerations
Gonadotropin treatment has been used in fertility treatment since the 1930s. First, preparations coming from animals were injected, then, gonadotropins prepared from the pituitary glands of human cadavers. A great step was achieved with the introduction of human menopausal gonadotropin extracted from the urine of postmenopausal women. When cases of Creutzfeld-Jacob disease were recognized after...
متن کاملA cost-effectiveness evaluation comparing originator follitropin alfa to the biosimilar for the treatment of infertility
OBJECTIVES To perform a cost-effectiveness evaluation comparing the originator follitropin alfa (Gonal-f®) to the biosimilar (Bemfola®) in the Italian and Spanish contexts, with an assessment of the German and UK backgrounds. METHODS Starting from the study by Rettenbacher et al, a cost-effectiveness model was developed in the Italian and Spanish contexts. Clinical data on subjects, doses of ...
متن کاملA new treatment for polycythemia vera: recombinant interferon alfa.
Recombinant interferon alfa, a natural product with growth inhibitory capabilities, has been demonstrated for the first time to have significant therapeutic efficacy in controlling the red cell mass in patients with the myeloproliferative disease polycythemia vera. The starting dose was 3.0 X 10(6) U three times a week, subcutaneously (SC). In three patients the dose required was 5.0 X 10(6), U...
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ژورنال
عنوان ژورنال: Biologics: Targets & Therapy
سال: 2009
ISSN: 1177-5475
DOI: 10.2147/btt.s3326