Recent Updates on the Synthesis of Bioactive Quinoxaline-Containing Sulfonamides

Quinoxaline is a privileged pharmacophore that has broad-spectrum applications in the fields of medicine, pharmacology and pharmaceutics. Similarly, sulfonamide moiety considerable interest medicinal chemistry, as it exhibits wide range pharmacological activities. Therefore, therapeutic potential biomedical quinoxalines have been enhanced by incorporation group into their chemical framework. The present review surveyed literature on preparation, biological activities structure-activity relationship (SAR) quinoxaline derivatives due to broad activities, such diuretic, antibacterial, antifungal, neuropharmacological, antileishmanial, anti-inflammatory, anti-tumor anticancer action. current diagnostic findings this suggest quinoxaline-linked hybrids are capable being established lead compounds; modifications may give rise advanced agents against variety diseases.