Recent developments in the treatment of transfusion dependent thalassaemia

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Liver disease in transfusion dependent thalassaemia major.

AIMS To study the prevalence and severity of liver diseases of transfusion dependent thalassaemia major patients, and correlate the histological and biochemical changes of iron overload in liver with the peripheral blood markers. METHOD Liver biopsy was performed to assess the histological changes and liver iron content (LIC). RESULTS One hundred patients were evaluated (median age 11.7 yea...

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Endocrine complications in transfusion dependent thalassaemia in Penang Hospital.

Frequent blood transfusions can lead to iron overload which may result in several endocrine complications especially in the absence of adequate chelation therapy. The objectives of this study are to determine the prevalence of endocrine complications in transfusion dependent thalassaemia patients and the correlation of endocrine complications with the degree of iron chelation. This retrospectiv...

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ژورنال

عنوان ژورنال: Ceylon Medical Journal

سال: 2020

ISSN: 2386-1274,0009-0875

DOI: 10.4038/cmj.v65i3.9183