Recent advances in understanding urethral lichen sclerosus

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Recent advances in understanding urethral lichen sclerosus

Lichen sclerosus affecting the male genitalia is a poorly understood but potentially devastating condition. The natural history of the condition is beginning to be understood better with longer follow-up of patients. Recent long-term data suggest that circumcision for lichen sclerosus limited to the prepuce may not be curative as was once thought. In addition, surgical treatments should be foll...

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Lichen sclerosus of the male genitalia and urethral stricture diseases.

INTRODUCTION The true incidence of urethral involvement in patients with genital lichen sclerosus (LS) is unknown. We review the epidemiology and discuss the pathogenesis of LS and urethral stricture diseases. MATERIALS AND METHODS During the period 1991-2002, of 925 patients who underwent urethroplasty for anterior urethral stricture, 130 patients (14%) received the diagnosis of LS. In all p...

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Incidence and Pathogenesis of Urethral Involvement Due to Lichen Sclerosus

Recent findings Depending on the length and severity of urethral involvement, surgical management of lichen sclerosus urethral strictures can range from a simple meatotomy to a single or complex staged long repair using oral mucosa. Skin grafts or flaps are not recommended because skin could be involved by the disease. Perineal urethrostomy may represent the salvage solution in severe panurethr...

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Review of the male genital lichen sclerosus and urethral involvement

Lichen sclerosus (LS) previously known as balanitis xerotica obliterans, is a chronic, progressive lymphocyte mediated skin disease. It shows a predilection for the male genital area and may involve in external urinary meatus, penile urethra and even bulbar urethra causing stricture. Male genital lichen sclerosus (MGLSc) may lead to a significant impairment of urinary and sexual function; and i...

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Extragenital bullous lichen sclerosus.

Lichen sclerosus is an inflammatory skin condition characterized by inflammation of the papillary dermis that leads to white scarlike plaques. It occurs classically in the genitals but also has extragenital manifestations with a variety of clinical presentations including a bullous variant. The purpose of this review is to characterize extragenital bullous lichen sclerosus, suggest that it may ...

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ژورنال

عنوان ژورنال: F1000Research

سال: 2016

ISSN: 2046-1402

DOI: 10.12688/f1000research.7120.1