Recent advances in the treatment of triple-negative breast cancer
نویسندگان
چکیده
Triple-negative is the rarest breast cancer biological subtype of cancer, but has most aggressive course. The resuls chemotherapy, especially in advanced disease, are unsatisfactory. Numerous clinical trials have been conducted, that resulted registrations new drugs decreasing risk recurrence and improving outcome patients with metastatic disease. article summarizes data on modern therapies registered recent years. role pembrolizumab perioperative treatment early stage was indicated, as well importance olaparib BRCA mutation carriers. Additionally, indication for immunotherapy (pembrolizumab atezolizumab), sacituzumab govitecan PARP inhibitors (olaparib talazoparib) carriers were highlighted.
منابع مشابه
Recent advances in managing triple-negative breast cancers
Triple-negative breast cancer (TNBC) has been recently recognized as an important subgroup of breast cancer with a distinct outcome and therapeutic approach compared with other breast cancer subgroups. Because TNBC is defined by the absence of a target (either hormone receptors or HER-2), conventional cytotoxic therapy is still the mainstay of treatment. This report focuses on the current state...
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ژورنال
عنوان ژورنال: Oncology in Clinical Practice
سال: 2023
ISSN: ['2450-1654', '2450-6478']
DOI: https://doi.org/10.5603/ocp.2022.0056