Recent advances in chronic granulomatous disease
نویسندگان
چکیده
منابع مشابه
Recent advances in understanding and treating chronic granulomatous disease
A number of recent advances have been made in the epidemiology and treatment of chronic granulomatous disease. Several reports from developing regions describe the presentations and progress of local populations, highlighting complications due to Bacillus Calmette-Guérin vaccination. A number of new reports describe complications of chronic granulomatous disease in adult patients, as more survi...
متن کاملChronic granulomatous disease: recent advances in pathophysiology and treatment.
Chronic granulomatous disease (CGD) was characterised half a century ago as a primary immunodeficiency disorder of phagocytic cells resulting in failure to kill a specific spectrum of bacteria and fungi and in concomitant hyperinflammation with widespread tissue granuloma formation. CGD now comprises five genetic defects, each impairing one of five essential subunits of the phagocyte NADPH oxid...
متن کاملAdvances in Host Defense Mechanisms. Vol. 3. Chronic Granulomatous Disease
In the 1950s and early 1960s, there were several clinical publications describing children who had repeated bacterial infections, hypergammaglobulinemia, leukocytosis, and generalized granulomatous lesions. This disease was called "fatal chronic granulomatous disease of childhood" (FCGDC). In 1967, Paul Quie and his associates at the University of Minnesota showed that the polymorphonuclear leu...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Genes & Diseases
سال: 2020
ISSN: 2352-3042
DOI: 10.1016/j.gendis.2019.07.010