Recent advancements in combination subunit vaccine development

Recent Advances in Subunit Vaccine Carriers

The lower immunogenicity of synthetic subunit antigens, compared to live attenuated vaccines, is being addressed with improved vaccine carriers. Recent reports indicate that the physio-chemical properties of these carriers can be altered to achieve optimal antigen presentation, endosomal escape, particle bio-distribution, and cellular trafficking. The carriers can be modified with various antig...

Recent Advancements in Speech Enhancement

Speech enhancement is a long standing problem with numerous applications ranging from hearing aids, to coding and automatic recognition of speech signals. In this survey paper we focus on enhancement from a single microphone, and assume that the noise is additive and statistically independent of the signal. We present the principles that guide researchers working in this area, and provide a det...

Recent Advancements in Digital Forensics

Recent update in HIV vaccine development

Despite the tremendous efforts to develop a successful human immunodeficiency virus (HIV) vaccine, the quest for a safe and effective HIV vaccine seems to be remarkably long and winding. Disappointing results from previous clinical trials of VaxGen's AIDSVAXgp120 vaccine and MRKAd5 HIV-1 Gag/Pol/Nef vaccine emphasize that understanding the correlates of immune protection in HIV infection is the...

Recent Advances in Zika Virus Vaccine Development

Symbiosis Group Figure 1: Three different mechanisms of ADE (Antibody-dependent enhancement): A-receptors on virus particles bound by cross-reactive antibody get conformational change in structure that results in high affinity with the corresponding receptor on the host cell membrane. The corresponding receptor was not able to recognize the viral receptor before this conformational change. BThe...