Reborn Workhorse, CT, Pulls the Wagon Toward Thrombolysis Beyond 3 Hours
نویسندگان
چکیده
منابع مشابه
Reborn workhorse, CT, pulls the wagon toward thrombolysis beyond 3 hours.
Computed tomography (CT) is the time-honored workhorse of every emergency room and has revolutionized the speed and accuracy of the diagnosis of stroke. It is used to select patients for thrombolysis, the only approved drug treatment for ischemic brain infarction. However, the criteria for eligibility are very restrictive, notably with respect to the accepted 3-hour window. Only in a few center...
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BACKGROUND Outcome of stroke patients selected with cerebral computed tomography for intravenous thrombolysis administered in clinical routine from 3 to 4.5 hours after symptoms onset is not well investigated. Aim of this single-center, prospective, observational study was to compare the safety and efficacy of intravenous alteplase given in routine clinical praxis 181-270 minutes (late) and wit...
متن کاملIntra-arterial thrombolysis within 3 hours: where is the evidence?
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BACKGROUND AND PURPOSE Recombinant-activated factor VII (rFVIIa) is an investigational treatment for intracerebral hemorrhage (ICH). We have evaluated the drug's treatment effect based on time to treatment. METHODS ICH patients treated up to 4 hours from symptom onset were divided based on time to treatment: <or=3 hours (3H) and 3 to 4 hours (4H). Head CT was done at baseline and 24 hours. Ou...
متن کاملSafety and Clinical Outcome of Thrombolysis in Ischaemic Stroke Using a Perfusion CT Mismatch between 3 and 6 Hours
OBJECTIVE It may be possible to thrombolyse ischaemic stroke (IS) patients up to 6 h by using penumbral imaging. We investigated whether a perfusion CT (CTP) mismatch can help to select patients for thrombolysis up to 6 h. METHODS A cohort of 254 thrombolysed IS patients was studied. 174 (69%) were thrombolysed at 0-3 h by using non-contrast CT (NCCT), and 80 (31%) at 3-6 h (35 at 3-4.5 h and...
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ژورنال
عنوان ژورنال: Stroke
سال: 2004
ISSN: 0039-2499,1524-4628
DOI: 10.1161/01.str.0000115165.43847.ed