Reactive Species Metabolism and Cytotoxicity of Tribulus terrestris L. Alkaloid Extracts in Leukemic Cell Line

Cytotoxicity on human leukemic and rat hepatoma cell lines of alkaloid extracts of Psychotria forsteriana.

Study the Biological Activities of Tribulus Terrestris Extracts

In this study the extracts of the Iraqi herb Tribulus terrestris (Al-Hassage or Al-Kutub) was done by using of polar and non polar solvents, then the biological activity of these extractants was studied in three fields, First, the antibacterial activity (in vitro) on gram positive bacteria (Staphylococcus aureus), and gram negative bacteria (E. coli, Proteus vulgaris, Pseudomonas aerugiuosa, an...

Vinca alkaloid-induced tubulin spiral formation correlates with cytotoxicity in the leukemic L1210 cell line.

The ability of a class of C-20' modified vinca alkaloid congeners to induce tubulin spiral formation was investigated relative to their ability to inhibit microtubule assembly, their cytotoxicity against a leukemic cell line, L1210, and their measured and calculated partition coefficients. These studies were prompted by the observation that the energetics of vinca alkaloid-induced tubulin spira...

A Review on the Ayurvedic Herb Tribulus Terrestris L.

Gokhshura (Tribulus Linn) of Family Zygophyllaceae is an indigenous plant which has been mentioned in Ayurveda with several clinical properties. The plant finds use in one form or the other in various ayurvedic preparations and this has been made it necessary to review the various studies carried out in its chemistry as well as pharmacology.

Overexpression of microRNA-630 in Acute Leukemic T-cell line

Background: MicroRNAs (miRNAs) are noncoding RNAs that control the expression of their target mRNAs. It affects cancer cell proliferation and apoptosis as oncogenes or tumor suppressors. Dysregulation of miRNAs expression leads to the development of various cancers. Therefore, for the first time in this field, this study investigated the effect of overexpression of microRNA-630 on the Jurkat ce...