Reaching out

Reaching out for signals

ErbB1 receptors situated on cellular filopodia undergo systematic retrograde transport after binding of the epidermal growth factor (EGF) and activation of the receptor tyrosine kinase. Specific inhibitors of the erbB1 receptor tyrosine kinase as well as cytochalasin D, a disruptor of the actin cytoskeleton, abolish transport but not free diffusion of the receptor-ligand complex. Diffusion cons...

Reaching Out with Physical Chemistry.

P chemistry has been playing an important role in modern science as it contributes to the basic understanding of physical and chemical processes and bridges several scientific disciplines. From materials to analytical methods, from energy to the environment, and from biomimetics to biological systems, one employs the principles of physical chemistry to elucidate physical processes and explore n...

Reaching out to young investigators.

I t is self-evident that the future of biomedical research depends on the development of the next generation of investigators. Supporting young investigators has always been a core mission of the American Heart Association, one of its most distinguished and noble accomplishments. As an official journal of the American Heart Association, the editors and I think that Circulation Research must als...

Teen sexuality. Reaching out in the malls.

BACKGROUND Existing sexual health programs have not significantly reduced teen pregnancies or sexually transmitted diseases. A more creative approach is needed. METHODS An assessment of 539 teens in one Ontario city was conducted to identify knowledge about and use of birth control, comfort in discussing sexual health, and preferred sites, providers and methods of service delivery. RESULTS ...

Reaching Out to Shape Our Future