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Invited Review

Opioids, the wonderful analgesics, remain the mainstay in the clinical management of moderate to severe pain. However, development of analgesic tolerance and increase in pain sensitivity are some of the major concerns following opioid treatment. Studies suggest that NMDA receptor-mediated intracellular events play a role in mediating these effects. Moreover, NMDA receptor antagonists effectivel...

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Mechanical Properties of Irregular Fiber (Invited Review Paper)

Irregularities are inherent to virtually all fibers, including the conventional textile fibers, the high-performance brittle fibers and newly developed nano-fibers. These irregularities can fall into two main categories: dimensional or geometrical irregularity (external) and structural irregularity (internal). For natural fibers such as wool, diameter variation along fiber length is atypical ex...

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Invited Review Pregledni Članak Po Pozivu Invited Review

Epilepsy is a chronic neurological disorder characterised by recurrent epileptic seizures. Understanding the mechanisms by which it initiates and develops, as well as its modulating factors, are of great scientifi c interest. Experimental models of epilepsy are useful for understanding these mechanisms. Homocysteine, an amino acid endogenously generated in the body, together with its reactive m...

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Invited Review Nutritional genomics

Stover, Patrick J. Nutritional genomics. Physiol Genomics 16: 161–165, 2004; 10.1152/physiolgenomics.00204.2003.—The integration of genomics into nutritional sciences has illuminated the complexity of genome responses to nutritional exposures while offering opportunities to increase the effectiveness of nutritional interventions, both clinical and population based. Nutrients elicit multiple phy...

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Invited Review Articles

Although many proteases exist in human placenta, their physiological roles are still largely unknown. Our studies showed that these placental proteases metabolize vasoactive and immunomodulating peptides, possibly derived from the fetus, and control the exchange of peptide hormones across the placenta in order to maintain feto-placental homeostasis. We clarified the pregnancy serum oxytocinase ...

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ژورنال

عنوان ژورنال: The Bulletin of the Royal College of Surgeons of England

سال: 2013

ISSN: 1473-6357,1478-7075

DOI: 10.1308/147363513x13690603820702