RCARE: RNA Sequence Comparison and Annotation for RNA Editing
نویسندگان
چکیده
منابع مشابه
RNA Editing RNA
RNA Editing RNA editing is a term used to describe a diverse set of phenomena in which mRNA, rRNA, and tRNA transcripts are modified in sequence after transcription. The types of RNA editing vary from uridine (U) or cytidine (C) insertions and deletions within coding regions of mitochondrial mRNAs to the substitution of specific C residues with U residues in plant mitochondrial mRNAs or the sub...
متن کاملSequence based identification of RNA editing sites.
RNA editing diversifies the human transcriptome beyond the genomic repertoire. Recent years have proven a strategy based on genomics and computational sequence analysis as a powerful tool for identification and characterization of RNA editing. In particular, analysis of the human transcriptome has resulted in the identification of thousands of A-to-I editing sites within genomic repeats, as wel...
متن کاملComparison of Insertional RNA Editing in Myxomycetes
RNA editing describes the process in which individual or short stretches of nucleotides in a messenger or structural RNA are inserted, deleted, or substituted. A high level of RNA editing has been observed in the mitochondrial genome of Physarum polycephalum. The most frequent editing type in Physarum is the insertion of individual Cs. RNA editing is extremely accurate in Physarum; however, lit...
متن کاملGenome annotation in the presence of insertional RNA editing
MOTIVATION Insertional RNA editing renders gene prediction very difficult compared to organisms without such RNA editing. A case in point is the mitochondrial genome of Physarum polycephalum in which only about one-third of the number of genes that are to be expected given its length are annotated. Thus, gene prediction methods that explicitly take into account insertional editing are needed fo...
متن کاملRNA editing.
RNA editing is a term describing a variety of novel mechanisms for the modification of nucleotide sequences of RNA transcripts in different organisms. These editing events include (a) the U-insertion and -deletion type of editing found in the mitochondrion of kinetoplastid protozoa, (b) the C-insertion editing found in the mitochondrion of Physarum, (c) the C-to-U substitution editing of the ma...
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ژورنال
عنوان ژورنال: BMC Medical Genomics
سال: 2015
ISSN: 1755-8794
DOI: 10.1186/1755-8794-8-s2-s8