RbfA and IF3 couple ribosome biogenesis and translation initiation to increase stress tolerance
نویسندگان
چکیده
منابع مشابه
construction and validation of translation metacognitive strategy questionnaire and its application to translation quality
like any other learning activity, translation is a problem solving activity which involves executing parallel cognitive processes. the ability to think about these higher processes, plan, organize, monitor and evaluate the most influential executive cognitive processes is what flavell (1975) called “metacognition” which encompasses raising awareness of mental processes as well as using effectiv...
Eukaryotic initiation factor 6 mediates a continuum between 60S ribosome biogenesis and translation.
Eukaryotic ribosome biogenesis and translation are linked processes that limit the rate of cell growth. Although ribosome biogenesis and translation are mainly controlled by distinct factors, eukaryotic initiation factor 6 (eIF6) has been found to regulate both processes. eIF6 is a necessary protein with a unique anti-association activity, which prevents the interaction of 40S ribosomal subunit...
متن کاملRibosome biogenesis and the translation process in Escherichia coli.
Translation, the decoding of mRNA into protein, is the third and final element of the central dogma. The ribosome, a nucleoprotein particle, is responsible and essential for this process. The bacterial ribosome consists of three rRNA molecules and approximately 55 proteins, components that are put together in an intricate and tightly regulated way. When finally matured, the quality of the parti...
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The association-dissociation kinetics of Escherichia coli MRE 600 “tight” (Type A) ribosomes (30 S + 50 S e 70 S ) for a variety of conditions have been studied in a light-scattering stopped-flow apparatus. The rate constants for the M&’-induced subunit association and 70 S dissociation reactions were 1.7 X lo’ M” s-’ (18 n m M&’) and 0.015 s-l (1 m M@’), respectively. The addition of ribosomal...
متن کاملThe fidelity of translation initiation: reciprocal activities of eIF1, IF3 and YciH.
Eukaryotic initiation factor eIF1 and the functional C-terminal domain of prokaryotic initiation factor IF3 maintain the fidelity of initiation codon selection in eukaryotes and prokaryotes, respectively, and bind to the same regions of small ribosomal subunits, between the platform and initiator tRNA. Here we report that these nonhomologous factors can bind to the same regions of heterologous ...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 2019
ISSN: 0305-1048,1362-4962
DOI: 10.1093/nar/gkz1065