Randomised controlled trials in psychiatry

Introducing “Agreement on what to Measure in Randomised Controlled Trials in Burn Care” Research Project

پروژه پژوهشی "توافق درباره‌ی پیامدهای قابل اندازه‌گیری در کارآزمایی های کنترل‌دار مربوط به مراقبت‌های سوختگی" توسط گروهی از پژوهش‌گران با تجربه، در حوزه سوختگی، زیر نظر دکتر Young از کشور انگلستان در حال انجام می‌باشد. هدف نهایی از انجام این مطالعه، تهیه و تدوین مجموعه‌ای از پیامدهای اساسی (core outcome set (COS)) است که در گزارش کارآزمایی های شاهد‌دار تصادفی مربوط به مراقبت‌های سوختگی باید مور...

[Randomized controlled trials in psychiatry].

In the past twenty years, evidence based medicine (EBM) has become a dominant paradigm of the contemporary medical practice. Since the emergence of the significant article by Geddes and Harrison in 1997, this doctrine has become part of psychiatry too. According to the rules of EBM, the most valuable clinical data comes from randomized-controlled trials (RCT). Nevertheless there are numerous re...

Randomised controlled trials.

Alternatives to placebo-controlled trials in psychiatry

Patients receiving placebo do not merely receive an inert substance but also receive support, concern, and reassurance that assists the therapeutic alliance and encourages the positive attitude that forms the basis of cognitive treatment. Response to non-specific factors is seen in all fields of medicine but is particularly potent in psychiatry. The placebo response is variable across settings ...

Blindness in Randomized Controlled Trials

In combination with randomization, blinding or masking is an important factor in randomized controlled trials (RCTs), particularly in trials that assess therapeutic effects. Here an attempt is made to explain blindness and why it is important. In clinical trials, blinding is defined as the condition imposed on a study in which study participants, health care providers and assessors collecting o...