Rafael Heliodoro Valle (1891-1959)

Otto Mangold (1891-1962)

Otto Mangold [5] was an early-twentieth-century embryologist who specialized in the development of amphibian embryos. A major emphasis of his research was refining the concept of the organizer [6], now referred to as embryonic induction [7]. He was born on 4 November 1891 in Auenstein, Germany, and came from what Viktor Hamburger [8], a colleague and personal acquaintance, described as ?peasant...

Alfred Henry Sturtevant (1891?1970)

Alfred Henry Sturtevant studied heredity in fruit flies in the US throughout the twentieth century. From 1910 to 1928, Sturtevant worked in Thomas Hunt Morgan?s research lab in New York City, New York. Sturtevant, Morgan, and other researchers established that chromosomes play a role in the inheritance of traits. In 1913, as an undergraduate, Sturtevant created one of the earliest genetic maps ...

Dmd065755 1891..1904

The cytochrome P450 2C19 (CYP2C19) enzyme plays an important role in the metabolism of many commonly used drugs. Relatively little is known about CYP2C19 inhibitors, including compounds of natural origin, which could inhibit CYP2C19, potentially causing clinically relevant metabolism-based drug interactions. We evaluated a series (N = 49) of structurally related plant isoquinoline alkaloids for...

Volker Kaibel and Rafael Mechtel

We introduce revlex-initial 0/1-polytopes as the convex hulls of reverse-lexicographically initial subsets of 0/1-vectors. These polytopes are special knapsack-polytopes. It turns out that they have remarkable extremal properties. In particular, we use these polytopes in order to prove that the minimum numbers gnfac(d, n) of facets and the minimum average degree gavdeg(d, n) of the graph of a d...

Rafael Lorente de No, 1946