Radioimmunolocalization of human colorectal carcinoma xenografts with the F(ab')2 fragment of an anti-sialyl Lewis a monoclonal antibody and clinical radioimmunoscintigraphy of recurrent rectal carcinoma patient
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an investigation of the types of text reduction in subtitling: a case study of the persian film gilaneh with english subtitles
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15 صفحه اولRadioimmunoscintigraphy of colorectal carcinoma using technetium-99m-labeled, totally human monoclonal antibody 88BV59H21-2.
Radioimmunoscintigraphy (RIS) using human monoclonal antibodies offers the important clinical advantage of repeated imaging over murine monoclonal antibodies by eliminating the cross-species antibody response. This article reports a Phase I-II clinical trial with Tc-99m-labeled, totally human monoclonal antibody 88BV59H21-2 in patients with colorectal carcinoma. The study population consisted o...
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The B72.3 reactive antigen, TAG-72, has been purified and a series of second generation monoclonal antibodies (MAbs), designated CC (colon cancer), have been characterized by a range of in vitro immunological assays. Six CC MAbs (CC11, CC30, CC46, CC49, CC83, and CC92) were chosen for analyses of the in vivo binding to a human colon carcinoma xenograft. All 6 MAbs were previously shown to be di...
متن کاملRadioimmunolocalization of human gastric carcinoma xenografts SY 86 B and SY 86 D with 131I-labeled monoclonal antibody.
The suitability of individual MAb for application in vivo should be carefully confirmed. The monoclonal antibody GL-013, with specific binding reactivity in vitro to human tumors of the gastrointestinal tract, was radioiodinated and injected intraperitoneally into nude mice bearing human gastric carcinoma xenografts SY 86 B (moderately differentiated glandular adenocarcinoma) and SY 86 D (signe...
متن کاملRadioimmunoscintigraphy of Breast Tumor Xenografts in Mouse Model by 99mTc Direct Radiolabeling of a Monoclonal Antibody PR81
Introduction: The radioimmunoscintigraphy (RIS) has found widespread clinical applications in tumor diagnosis. Human epithelial mucin, MUC1, is commonly over expressed in adenocarcinoma including 80% of breast cancers and represents a useful target for RIS. The PR81 is a new murine anti-MUC1 monoclonal antibody that was found to react with the membrane extracts of se...
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ژورنال
عنوان ژورنال: Annals of Cancer Research and Therapy
سال: 1993
ISSN: 1344-6835,1880-5469
DOI: 10.4993/acrt1992.2.199