Radioimmunoassay of gastrin
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چکیده
منابع مشابه
Radioimmunoassay of Gastrin
Radioimmunoassays have recently made it possible to measure the concentration of gastrin in human plasma (Hansky and Cain, 1969; Byrnes, Young, Chisholm, and Lazarus, 1970; McGuigan and Trudeau, 1970; Yalow and Berson, 1970). It has been shown that the plasma gastrin rises in response to such stimuli as the ingestion of food and insulin hypoglycaemia. However, little is known about any quantita...
متن کاملRadioimmunoassay of gastrin: studies in pernicious anaemia.
Serum gastrin levels in patients with pernicious anaemia were measured by immunoassay in the fasting state, following gastric perfusion with 0.9% saline, 0.1N hydrochloric acid, and solutions of increasing acidity, and after the intravenous injection or infusion of secretin. The fasting serum gastrin level was measured in 21 patients with pernicious anaemia and found to be elevated at 1,036 +/-...
متن کاملEffect of food on serum gastrin evaluated by radioimmunoassay.
The effect of food on serum gastrin in normal man has been evaluated by radioimmunoassay. Protein and amino acids produced up to a five-fold increase in serum gastrin levels, followed in potency by alcohol, fat, and glucose. Distilled water did not stimulate the release of gastrin. An injection of atropine sulphate (0.6 mg) augmented the response to all good stimuli but in itself did not affect...
متن کاملEvaluation of two commercial kits for serum gastrin assay, and comparison with a conventional radioimmunoassay procedure.
We compared two gastrin radioimmunoassay kits ("Immutope" kit, Squibb & Co.; "Gastrin R.I.A." kit, Schwarz/Mann) to the conventional gastrin radioimmunoassay of Yalow and Berson [Gastroenterology 58, 1 (1970)] as run by us and by a second reference laboratory. Although both kits were found to effectively discriminate above-normal and normal values for serum gastrin, they significantly underesti...
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ژورنال
عنوان ژورنال: Gastroenterology
سال: 1970
ISSN: 0016-5085
DOI: 10.1016/s0016-5085(70)80086-5