Radiographic changes of the skull in sickle cell anemia

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Side Effects of Hydroxyurea in Patients with Sickle Cell Anemia

Background: Hemoglobin S arises is the result of a point mutation (A-T) in the sixth codon on the -globin gene on chromosome 11 causing sickle cell anemia. The presence of fetal hemoglobin in infancy plays a relatively protective role for vaso-occlusive symptoms that are the major contributor for the morbidity and mortality among patients with sickle cell anemia. hydroxyurea, an s-phase-specif...

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The Effect of L-Glutamine on Pain Crisis Reduction in Patients with Sickle Cell Anemia and Sickle β°-Thalassemia

Background: A low level of L-glutamine, a precursor of nicotinamide adenine dinucleotide (NAD) in red blood cells (RBCs), is identified as an underlying mechanism for the potential decrement of the NAD redox and the incidence of pain crisis in sickle cell anemia (SCA). The aim of this study is to assess the impact of oral L-glutamine therapy on pain crisis reduction in patients with SCA and sic...

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Mandibular bone changes in sickle cell anemia: fractal analysis.

OBJECTIVES The radiographic changes of mandibular bone texture was evaluated in patients with sickle cell anemia (SCA) and healthy controls. Fractal analysis was employed. STUDY DESIGN Thirty-five individuals (age range 11 to 40 years) who had been diagnosed as having homozygous SCA were enrolled as the patient group. Twenty-six healthy individuals within the same age range constituted the co...

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ژورنال

عنوان ژورنال: American Journal of Roentgenology

سال: 1979

ISSN: 0361-803X,1546-3141

DOI: 10.2214/ajr.132.3.373